The school was established in the year 1967 by the then head of state Dr. Kwame Nkrumah.
It was the second secondary technical school after Ghana Secondary Technical School (GSTS) in Takoradi.
It also bore the name Ghana Secondary Technical School until in the 2000s that it was changed to Koforidua Secondary Technical School and finally to Koforidua Senior High Technical School in 2012.
It previously gave the chance to people who did not attend the school to further their studies by pursuing the A-level.
Due to its beauty and conserved nature, it earned the name Eastern Varsity.
In addition, the site plan of the school was believed to have been developed purposely to be used as the first public university in the Eastern Region of Ghana, but could not reach fruition.
The school was started as a boys school but still had some girls pursuing the A-level.
This brought about the idea that some girls were interested in the technical courses and so the school started admitting girls.
The school was basically set up to feed the Kwame Nkrumah University of Science and Technology (KNUST).
As of December 2011, the school has over 2,200 students.
The school existed as a Boys School since its establishment, until recently few girls were introduced of about 5% of the overall students population.
Because of the initial boy population, the slogan Mmarima Mma really sufficed which means when transliterated, Sons of Men. (It is an Akan (Twi) language.)
The number increased much within the time-period of the 4-year schooling program that was introduced by the Ghana Education Service.
Sec-Tech has over 120 active teachers and about 90 non-teaching staffs who are dedicated in providing the best available services to their students.
The school is headed (known as Headmaster) by Mr. S.P. Foli (the first old boy to be appointed)who took over from Mr. Bempong J.K who hails from Akwatia (as at the time of writing), born in 1953.
He headed this institute for over 9 years.
The school has the largest stretch of land in Koforidua, if not the whole of Eastern Region.
Most and bigger sporting events are held often in the school because of her spacious environment.
Sources : Wikipedia.com and http://African-research.com